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InterSpace Knee

Infection to Correction

The most widely studied spacer technology in the world, InterSpace® is the first pre-formed spacer with 96.1 percent eradication rate.1

InterSpace Knee is designed to temporarily replace an infected implant during a total knee arthroplasty and provide the patient with mobility and predictable, consistent local antibiotic release.2,4


  • Gentamicin-impregnated PMMA bone cement
  • Offers functional success rates equal to non-infected revisions3
  • The ability to shorten O.R. time4,5
  • Various sizes



  1. Romano CL, Drago L, Logoluso N. Low-dose gentamicin-loaded spacers are effective for two-stage revision.  Musculoskeletal Infection Society (MSIS).  2013 July 30.
  2. Bertazzoni Minelli E, Benini A, Magnan B, Bartolozzi P. Release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty. J Antimicrob Chemother. 2004 Feb;53(2):329-34. Epub 2003 Dec 19.
  3. Romano CL, Romano D, Logoluso N, Meani E. Aseptic versus total hip arthroplasty revision: comparing the results. Poster presented at the 76th annual American academy of Orthopaedics Surgeons Meeting; 2009 Feb. 25-28; Las Vegas, NV.
  4. Romano CL, Romano D, Meani E, Logoluso N, Drago L. Two-stage revision surgery with preformed spacers and cementless implants for septic hip arthritis: a prospective, non-randomized cohort study. BMC Infect Dis. 2011 May 16;11:129. doi: 10.1186/1471-2334-11-129.
  5. Pattyn C, De Geest T, Ackerman P, Audenaert E. Preformed gentamicin spacers in two-stage revision hip arthroplasty: functional results and complications. Int Orthop. 2011 Oct; 35 (10): 1471-6. Doi:10.1007/s00264-010-1172-8. Epub 2010 Nov 30.

    InterSpace® is produced by Tecres® S.p.A., Italy, and distributed in the United States exclusively by Exactech, Inc 
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